17-α-ethynylestradiol alters conversion of α-linolenic acid to longer chain PUFA in rat hepatocarcinoma cells
نویسندگان
چکیده
منابع مشابه
Conversion of α-linolenic acid to longer-chain polyunsaturated fatty acids in human adults
The principal biological role of α-linolenic acid (αLNA; 18:3n-3) appears to be as a precursor for the synthesis of longer chain n-3 polyunsaturated fatty acids (PUFA). Increasing αLNA intake for a period of weeks to months results in an increase in the proportion of eicosapentaenoic acid (EPA; 20:5n-3) in plasma lipids, in erythrocytes, leukocytes, platelets and in breast milk but there is no ...
متن کاملDietary α-linolenic acid, linoleic acid, and n-3 long-chain PUFA and risk of ischemic heart disease.
BACKGROUND n-3 (omega-3) PUFA has been proposed as having health-promoting effects, primarily in relation to ischemic heart disease (IHD). Whether these benefits can be achieved by both α-linolenic acid (ALA, 18:3n-3) and n-3 long-chain PUFA (LC-PUFA) is debatable. OBJECTIVE The objective was to examine the association between ALA intake and risk of IHD in healthy subjects and to see if this ...
متن کاملWhole-body retention of α-linolenic acid and its apparent conversion to other n-3 PUFA in growing pigs are reduced with the duration of feeding α-linolenic acid.
In the present study, fifteen growing pigs were used to determine the whole-body oxidation, retention efficiency (RE) and apparent conversion (AC) of α-linolenic acid (18 : 3n-3) to n-3 highly unsaturated fatty acids (HUFA), including EPA (20 : 5n-3) and DHA (22 : 6n-3). The pigs were fed a diet containing 10% flaxseed for 30 d. Whole-body fatty acid composition was determined at initial (27.7 ...
متن کاملα-Linolenic acid, linoleic acid and heart failure in women.
α-Linolenic acid (18 : 3n-3) intake and linoleic acid (18 : 2n-6) intake have been associated with lower rates of CHD, though results have not been consistent. The relationship of these fatty acids with incident heart failure (HF) is not well established. We examined the hypothesis that women with higher intakes of 18 : 3n-3 and 18 : 2n-6 would have lower rates of HF hospitalisation and mortali...
متن کاملOleic acid versus linoleic and α-linolenic acid. different effects on Ca2+ signaling in rat thymocytes.
BACKGROUND Oleic acid is the principal fatty acid of olive oil composition and is reported to play a crucial role in its healthy aspects. However, the detailed mechanism of action is poorly understood. AIMS This study aims to elucidate the role of oleic acid in calcium signaling in rat thymocytes, in comparison to linoleic and linolenic acid. METHODS Fatty acids were applied to thymocytes i...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 2011
ISSN: 0029-6651,1475-2719
DOI: 10.1017/s0029665111002850